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Radiation & Cancer Biology

The Radiation and Cancer Biology laboratories are located in the Medical Research Library building at Indiana University School of Medicine, Indianapolis, Indiana. The laboratories are well equipped for "state of the art" investigations at the cellular and molecular level both "in vitro" and "in vivo."  The cell biology laboratories contain tissue culture hoods, incubators, Coulter cell counters, inverted phase contrast microscopes, centrifuges, water baths, refrigerators, and -20 οC and -80 οC freezers.

The molecular biology labs are equipped to investigate a number of molecular endpoints, including: (Southern) DNA, (Northern) RNA, RNAse protection, (Western) protein analysis, DNA sequencing, PCR analysis, Pulse field gel electrophoresis, and gene promoter (Gel shift) analysis.

Facilities for cytogenetic endpoints utilizing fluorescent in situ hybridization (FISH) techniques are also available. The laboratories also have a designated 250 kVp X-ray machine and flow cytometer, located in the basement of the building.  As members of Indiana University's NCI-designated Cancer Center, both Drs. Mendonca and Dynlacht also have access to nearby flow cytometry, imaging, biochemistry, and animal core facilities. Currently several basic science and translational research topics are under investigation in the Mendonca and Dynlacht laboratories